Alebund Pharmaceuticals Announces Collaboration and License Agreement with R1 Therapeutics for AP306

AP306 is a first-in-class pan-phosphate transporter inhibitor in development for the treatment of hyperphosphatemia in patients with chronic kidney disease (CKD) receiving dialysis

Alebund grants exclusive rights to develop, manufacture, and commercialize AP306 outside Greater China to R1 Therapeutics, a newly launched company backed by leading global kidney care providers and life sciences strategic and venture capital investors

The collaboration includes potential milestone payments of up to low triple-digit millions of U.S. dollars and tiered royalties in the low double-digit percentage range based on net sales of AP306 in the licensed territory

Alebund holds a substantial non-dilutive equity interest in R1, with the opportunity to participate in future commercial upside through dividends

Shanghai, China – March 17, 2026 – Alebund Pharmaceuticals (“Alebund” or the “Company”), a leading renal-focused biopharmaceutical company, today announced that it has entered into licensing and equity agreements (the “Agreements”) with R1 Therapeutics, Inc. (“R1”). R1 is a newly launched clinical-stage biotechnology company that recently completed an oversubscribed Series A financing of $77.5M. R1 is backed by major global kidney care providers, DaVita, one of the largest kidney care providers globally, and U.S. Renal Care, the largest privately held dialysis provider in the United States and a syndicate of leading global venture capital investors.

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Alebund Reached Cooperation with Roche to Commercialize MIRCERA® In China

October 19 2023, Shanghai, China — Roche Pharmaceutical (hereinafter referred to as “Roche”) and Alebund Pharmaceuticals (hereinafter referred to as “Alebund”) entered a supply and marketing agreement, under which Alebund will exclusively promote Roche’s MIRCERA® (methoxy polyethylene glycol-epoetin beta) in mainland China.

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Alebund Pharmaceuticals and Peking University First Hospital enter into a strategic partnership to develop a novel and specific treatment for IgA Nephropathy (IgAN)

SHANGHAI/BEIJING, CHINA, June 30, 2022 — Alebund Pharmaceuticals, a biopharmaceutical company dedicated to developing innovative therapies for the treatment of renal diseases and related chronic conditions, announced a strategic partnership between its subsidiary Alezyme and Peking University First Hospital, to discover, develop and commercialize PKU308/AP308, a potential innovative and specific therapeutic for IgAN. Designed and developed by Peking University First Hospital, this compound has a completely innovative mechanism of action (MOA) as compared to currently available treatment options.

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Chugai and Alebund Enter into Option and License Agreement for EOS789 under Development for Hyperphosphatemia

Logos of Chugai and Alebund

Chugai Pharmaceutical Co., Ltd.
Alebund Pharmaceuticals (Hong Kong) Limited

  • Chugai and Alebund enter into an option and license agreement regarding EOS789, an investigational drug for hyperphosphatemia, discovered by Chugai
  • If Alebund decides to exercise the option, Chugai will grant to Alebund an exclusive license to develop, manufacture, and commercialize EOS789 worldwide including Japan

TOKYO, JAPAN and SHANGHAI, CHINA, July 9, 2021 — Chugai Pharmaceutical Co., Ltd. (TOKYO: 4519) and Alebund Pharmaceuticals (Hong Kong) Limited, announced that they have entered into an option and license agreement regarding Chugai’s EOS789, an investigational agent under development for hyperphosphatemia.

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